School of Medicine >   Division of Cancer Prevention >   Recent Publications

Publications

Recent papers

     1.  Foreman JE, Sorg JM, McGinnis KS,

         Rigas B, Williams JL, Clapper ML,

         Gonzalez FJ,Peters   JM. 

         Regulation of peroxisome  proliferator-   

         activated receptor-beta/delta by

         the APC/beta-CANTENIN pathway and

         nonsteroidal anti-inflammatory drugs.   Mol

         carcinog. 2009; in press

     2. Zhao W, Mackenzie GG, Murray OT, Zhang

         Z. Rigas B.   Phosphoaspirin (MDC-43), a  

         novel benzyl ester of aspirin, inhibits the

         growth of human cancer cell lines more

         potently than aspirin:  A redox-dependent effect.  Carcinogenesis 2009; 30:512-9 

             To view pdf click here.

    

      3. Sun Y, Chen J, Rigas B. Chemopreventive agents induce oxidative stress in

         cancer cells leading to COX-2 overexpression and COX-2-independent cell death.

         Carcinogenesis, 2009; 30:93-100

          To view pdf click here.

     4.  Zhou H, Huang L, Sun Y, Rigas B. Nitric oxide-donating aspirin inhibits the

         growth of pancreatic cancer cells through redox-dependent signaling.

         Cancer Lett, 2009; 273:292-9           

           To view pdf click here.

     5.  Sun Y, Rigas B. The thioredoxin system mediates redox-induced cell death in

         human colon cancer cells: Implications for the mechanism of action of anticancer

         agents.  Cancer Res, 2008; 68:8269-77  

          To view pdf click here.

     6. Rigas B, Kozoni V. The novel phenylester anticancer compounds: Study of a  

         derivative of aspirin (phoshoaspirin). Int J Oncol. 2008; 32:97-100.

         Rigas- Kozoni - Int J Oncol.-2008

         To view pdf click here.

     7. Williams JL, Ji P, Ouyang N, Liu X, Rigas B. NO-donating aspirin inhibits the

         activation of NF-kB in human cancer cell lines and Min mice. Carcinogenesis  2008;

         29:390-7

           To view pdf click here.

     8.   Wang Y, Zhou Y, Sokolov J, Rigas B, Levon K, Rafailovich M.

          potentiometric    protein sensor built with surface molecular imprinting method.           Biosens Bioelectron. 24:162-6

            To view pdf click here.

     9.  Rao  CV, Joseph S, Gao L, Patlolla J, Choi C-I, Kopelovich L, Steele VE,

         Rigas B.  Pharmacokinetic and pharmacodynamic study of NO-donating aspirin

         in F344 rats. Int J Oncol, 2008; 33:799-805

          To view pdf click here.

      

    10.   Jiang J, Li C, Lombardi J, Colby RH, Rigas B, Rafailovich MH, Sokolov JC. The

          effect of physiologically relevant additives on the rheological properties 

          of concentrated Pluronic copolymer gels. Polymer, 2008; 49:3561-3567

             To view pdf click here.

    11.  Yang K, Kurihara, N, Fan K, Newmark H, Rigas B, Bancroft L, Corner G,

           Livote E, Lesser M, Edelmann W, Velcich A, Lipkin M, Augenlicht L. Dietary

           inductionof colonic tumors in a mouse model of sporadic colon cancer. Cancer  

           Res, 2008;68:7803-10

    12.  Rigas B. Williams JL NO-donating NSAIDs and cancer: An overview with a

           note on whether NO is required for their action. Nitric Oxide. 2008; 19:199-204.

            To view pdf click here.

    13.  Rasheed S, Rigas B.  Screening for colorectal cancer: Does it all start with

          aberrant crypt foci? Gastrointestinal Endoscopy, 2008; 67:1103-5.

            To view pdf click here.

    14.  Rigas B, Rao CV, Cooney R, Singh S. Food components, alternative medicine

           and cancer: Progress and promise, Nutr Cancer, 2008; 60(S):1-1

    15. Rigas B, Sun Y. Induction of oxidative stress as a mechanism of action of

          chemopreventive agents against cancer. Br J Cancer, 2008; 98:1157-60.

            To view pdf click here.

    16.. Mackenzie GG, Rasheed S, Wertheim W, Rigas B. NO-donating NSAIDs,

         PPARδ and cancer: Does PPARδ contribute to colon carcinogenesis? PPAR Res,

         2008; 2008:919572.

          To view pdf click here.

 

Additional papers

      1.  Rigas B. The use of nitric oxide-donating nonsteroidal anti-inflammatory drugs

           in the chemoprevention of colorectal neoplasia.  Curr Opin Gastroenterol. 

           2007;23:55-9

            To view pdf click here.

      2.  Kashi K, Rigas B.  The mechanism of action of nitric oxide-donating aspirin.

           Biochem Biophys Res Commun. 2007;358:1096-101

           To view pdf click here.

      3.   McIlhatton MA, Tyler J, Burkholder S, Ruschoff J, Rigas B, Kopelovich L,

            Fishel R.  Nitric oxide-donating aspirin derivatives suppress microsatellite

            instability in mismatch repair-deficient and hereditary nonpolyposis colorectal

            cancer cells.  Cancer Res 2007;67:10966-75

             To view pdf click here.



     

 


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